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This epigenetic regulation upregulates NLRP3 inflammasome activity, which subsequently triggers tubular cell pyroptosis, thereby exacerbating tubular damage and the progression of DKD (166)
Intraoperative cytological findings in two cases of psammomatous melanotic schwannoma
MC4R in particular is expressed in hypothalamic nuclei controlling sexual behavior and present in spinal cord regions governing genital reflexes
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