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Patients who have started or maintained exercise programs may notice improved endurance and changes in body composition

An early dose-ranging trial tested five increasing doses of semaglutide and found that each dose increase led to greater weight loss, but two of the middle doses produced nearly the same result (11.6% and 11.2%), an early sign that going higher doesnt always yield a greater effect

Men report losing substantial amounts of body fat, like 41 pounds or more, while maintaining or even gaining muscle mass when the approach is structured correctly

doi: 10.2337/dc11-1465

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