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Anything that increases inflammation such as a lack of sleep, a diet high in inflammatory foods such as processed foods and sugar, smoking, or underlying infections, exposure to EMFs, an unhealthy gut, polluted indoor air or hidden mould
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Therefore, riboflavin deficiency will lead to the downregulation of GSH and oxidative stress, which is the predominant cause for reduced osteogenic capacities of BMSCs and enhanced osteoclastic potentials of osteoclast precursors [54, 55], finally leading to net bone loss
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