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Inclusion criteria were: (1) peer-reviewed original studies or systematic reviews investigating diabetes-related male reproductive dysfunction, (2) studies examining relevant molecular mechanisms such as oxidative stress, mitochondrial dysfunction, inflammation, apoptosis, and epigenetic alterations, and (3) research evaluating intervention strategies (e.g., antioxidants, hormonal treatments, lifestyle modifications)

Interferon regulatory factor 3 plays a role in macrophage responses to interferon-

These plateaus usually resolve spontaneously within two to four weeks

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