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12.1%), and 10% (6.4% vs 2.1%)
This enzyme is often overexpressed in adipose tissue in conditions of obesity and metabolic dysfunction, leading to the depletion of nicotinamide and reduced availability of NAD+
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Nuclear receptor coactivators 4 (NCOA4) mediated the autophagic degradation of ferritin in lysosomes, resulting in the release of free iron from ferritin to promote ferroptosis (Mancias et al., 2014)
Data availability All data generated or analyzed during this study are included in this published article and in the supplementary files
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