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Lets say that Medicaid negotiated an agreement to pay $4,000 a year for a semaglutide drug
The transition from tirzepatide to retatrutide is particularly interesting because tirzepatide already activates both GLP-1 and GIP receptors
Protein goes up, not down
Many telehealth GLP-1 providers set minimum BMI requirements of 27 or 30, which excludes people who want to use semaglutide for weight management but fall below those cutoffs
Butwhen you look at the ATTAIN-2 data in diabetic patients with obesity notoriously the hardest population to treat orforglipron produces better results, delivering 7.1% placebo-adjusted weight loss compared to injectable Wegovy's 6.2%
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