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GLP1RA , (2018 2) (insulin glargine + lixisenatide)

If weight loss occurs too rapidly without adequate protein intake or physical stimulus, the resulting muscle loss can leave joints like the knees and hips feeling less stable

But BPC-157 should not be positioned as a treatment that reverses advanced joint degeneration

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For instance, high doses of antioxidants like beta-carotene or vitamin E may not always be beneficial and could even exacerbate oxidative damage, particularly before exposure to harmful agents like radiation or cigarette smoke (51)