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PMID: 44 FriasJ
The CUPID (Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease) trial was the first gene therapy clinical study targeting SERCA2a in HF
Dunlop has received research support from Boehringer Ingelheim, Compass Pathways, NIMH, Otsuka, Sage, Usona Institute, and Takeda and has served as a consultant for Biohaven, Cerebral Therapeutics, Myriad Neuroscience, NRx Pharmaceuticals, Otsuka, and Sage
Evidence for its efficacy in people who are not biotin-deficient is limited
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