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There are several causes of vitamin B12 deficiency, including dietary factors, medical conditions, and genetic factors

doi: 10.1093/alcalc/agu010 Pubmed Abstract CrossRef Google Scholar View reference in article 56 KatarMDeveciHDeveciK

Critical Limitations Missing Pharmacokinetic Data: The researchers did not measure actual GHK-Cu concentrations in the brain

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These two cover the majority of the human bodys B12 needs