Elevated glutamine metabolism makes cancer cells more susceptible to glutamine deficiency caused by glutaminase inhibitors, which rapidly induces cell death [122]
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At the level of body composition, limited DEXA and CT evidence suggests that GLP-1RAs primarily reduce fat massspecifically visceral fatwhile relatively preserving lean mass (54, 75)
Olek RA, Samulak JJ, Sawicka AK, Hartmane D, Grinberga S, Pugovics O, Lysiak-Szydlowska W
It also remains unclear why the effects were specific for total ghrelin and not for acyl-ghrelin