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If dietary and hydration measures don't resolve constipation after one week, over-the-counter osmotic laxatives like polyethylene glycol (MiraLAX) are safe to use alongside semaglutide
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Gastrointestinal effects: Semaglutide commonly causes gastrointestinal adverse effects including nausea, vomiting, diarrhea, and constipation due to delayed gastric emptying
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Cardiovascular outcomes were evaluated using a prespecified composite endpoint
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