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Active inflammation, recent flares, or severe malnutrition generally contraindicate GLP-1 therapy
In such cases, switching to Tirzepatide may be worth considering
Luong TV, Abild CB, Bangshaab M, Gormsen LC, Sndergaard E
Structurally, Retatrutide is derived from the glucagon peptide backbone and incorporates targeted amino acid substitutions that improve resistance to enzymatic degradation while maintaining receptor binding capability
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