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Common Vitamin B12 deficiency symptoms Numbness, or tingling in the hands, legs, or feet, difficulty walking, anemia, a swollen, inflamed tongue, difficulty thinking and reasoning, or memory loss, weakness, and fatigue
For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.
The reticulocyte count (immature red blood cells) typically rises within 35 days of starting treatment, indicating that bone marrow is responding appropriately to therapy
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