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For context, most GLP-1 medications require consistent use for weeks or months to start working at full therapeutic capacity
The approval of injectable semaglutide for adolescents aged 12 and older in 2022 established a precedent for GLP-1-based weight management in younger patients, and an oral option could substantially change the treatment calculus for this population
Cagrilintide mechanism of action and pharmacology
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The rationale for combining them is mechanistic
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