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One possible explanation for this difference is that among various subconductance states of the channel (O1-O4), the Glu, ConA, and BPAM bound GluK2 represents the maximal conductance state (O4), while AMPAR structures represent lower (O1/O2) conductance states (Twomey et al., 2017a

2 Further research has also demonstrated that GST is expressed abundantly in tumor cells and associated closely to carcinogenesis, tumor formation, and chemotherapy resistance

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Cagrilintide is designed to mimic the natural hormone amylin, which plays a crucial role in appetite regulation, satiety, and blood sugar control