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For TH1-related cytokines, we also found a significant interactions between diet and treatment (diet and treatment interaction: F (1,54) = 8.136, R 2 = 0.102, p = 0.003) and the main effect of sex was also significant (main effect of sex: F (1,54) = 9.488, R 2 = 0.119, p = 0.001)

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It belongs to a novel class of agents known as triple agonists, meaning it simultaneously activates three distinct hormone receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor

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Treatment often requires addressing these biopsychosocial factors with a combination of medication, therapy, and 12-step programs (hence why its so complex), and its estimated that two-thirds of people relapse within the first six months